Cardiac Electromechanical Coupling Model of Myocardial Contractile Function under Ischemic Conditions
نویسندگان
چکیده
منابع مشابه
Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.
RATIONALE Perioperative myocardial ischemia is common in high-risk patients. The use of interventional revascularisation or even thrombolysis is limited in this patient subset due to exceedingly high bleeding risks. Blockade of voltage-gated sodium channels (VGSC) with lidocaine had been suggested to reduce infarct size and cardiomyocyte cell death in ischemia/reperfusion models. However, the i...
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We present a method for cardiac motion recovery using the adjustment of an electromechanical model of the heart to cine MRI. This approach is based on a proactive model which consists in a constrained minimisation of an energy coupling the model and the data. The presented method relies on specific image features in order to constrain the motion of the endocardia and epicardium and impose bound...
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BACKGROUND We hypothesized that (1) a significant proportion of ischemic dysfunctional segments that do not improve function will demonstrate postrevascularization contractile reserve and (2) electromechanical mapping (EMM) can identify segments that improve function as well as those with postrevascularization contractile reserve, a potential indicator of delayed functional improvement. METHO...
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Results: Results demonstrated that OC treatment or nicotine exposure led to increased hemorheological (blood viscosity, hematocrit and plasma viscosity), prothrombotic (plasminogen activator inhibitor-1), proinfl ammatory (Creactive protein, uric acid, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio) and anti-infl ammatory (corticosterone) markers. However, these effects except that o...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.11.578